What factors influence peptide binding to target proteins?

Peptide-protein interactions power biological processes everywhere. Signalling cascades. Immune responses. Enzymatic regulation. Grasping what controls these binding events matters for drug development and basic science. Whether peptides successfully grab target proteins with decent affinity and specificity depends on multiple factors. Five essential determinants control peptide binding to proteins, affecting affinity and specificity across different conditions, as explained on bluumpeptides.com. Amino acid composition Primary sequence sets … Continue reading What factors influence peptide binding to target proteins?